Start / Sit2026 NFL Week 6

Start

• Emanuel Wilson (RB, SEA) over Quinshon Judkins (RB, CLE). Zach Charbonnet (knee) is out Thursday night, handing Wilson the Seattle backfield, while Judkins did not practice on Wednesday, and he is dealing with an ankle injury ahead of a Ravens matchup.
• Germie Bernard (WR, PIT) over Keon Coleman (WR, BUF). Bernard just had his breakout game against the Colts with six catches for 80 yards on nine targets, and it helps that Roman Wilson (finger) and Michael Pittman (foot) are out, and the Buccaneers just allowed George Pickens and Ryan Flournoy to each score at least 12 PPR points in Week 5.
• Dameon Pierce (RB, PHI) over Woody Marks (RB, HOU). If Saquon Barkley sits, Pierce gets volume against the Panthers, who have surrendered 156.5 yards per game on the ground in 2026, while Marks faces a ferocious Jacksonville Jaguars front that has limited opposing running backs to a league-leading 10.6 fantasy points per game this year.

Sit

• Omarion Hampton (RB, LAC). In Week 5, Hampton played fewer snaps than both Keaton Mitchell and Kimani Vidal, and he ranks as RB36 in PPR scoring through five weeks.
• Michael Penix Jr. (QB, ATL). He completed regulation but did not play Atlanta's overtime possession after pain increased in his ribs, so keep Penix on the bench until practice participation and starting status are clear.

Flex of the Week

Xavier Worthy (WR, KC). If Rice is out then Worthy should be considered a starter in all three-receiver leagues, since Tyquan Thornton is on injured reserve and the Chargers have allowed six receivers to score at least 12.3 PPR points this season.